IgA-Dominant Postinfectious Glomerulonephritis: A New Twist on an Old Disease

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IgA-dominant postinfectious glomerulonephritis: a new twist on an old disease.

IgA-dominant acute postinfectious glomerulonephritis (APIGN) is an increasingly recognized morphologic variant of APIGN, particularly in the elderly. In contrast to classic APIGN, in which there is typically glomerular deposition of IgG and C3 or C3 only, IgA is the sole or dominant immunoglobulin in IgA-dominant APIGN. Because the vast majority of reported cases occur in association with staph...

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Clinicopathologic Features of IgA-Dominant Postinfectious Glomerulonephritis

BACKGROUND IgA-dominant acute postinfectious glomerulonephritis (APIGN) is a recently recognized morphologic variant of APIGN, but its clinicopathologic features were not clearly characterized. We will present demographic, clinical and renal biopsy findings from seven patients with IgA-dominant APIGN with a literature review. METHODS All renal biopsy specimens (n=1,119) processed by the Depar...

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IgA-Dominant Acute Postinfectious Glomerulonephritis Presenting as Acute Renal Failure in a Kidney Transplant Recipient

Manish Anand, Juan Pablo Arroyo, Hassan Alhalabi, Timothy Thayer, Mark Lusco, Anthony Langone and Beatrice P. Concepcion Division of Nephrology and Hypertension, Vanderbilt Center for Kidney Disease, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Department of Internal Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA; and Department of Pathology, Micro...

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Coexistant of Fabry Disease and IgA Glomerulonephritis in a 39 year old male

  Anderson-Fabry disease is a rare inherited X-linked lysosomal storage disease caused by deficiency of the enzyme alpha-galactosidase A. Hereby we report a 39 year old male that presented with proteinuria and edema. Histopathologic, immunofluorescence and ultrastractural examination of renal tissue were in favor  of  Fabry disease in associate with IgA nephropathy. Fabry's disease associated ...

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[Postinfectious glomerulonephritis in adults: a hidden face of an old disease].

The epidemiology of postinfectious GN has changed considerably during recent decades, especially in developed countries. This disease typically has occurred in children and most often following a respiratory tract or skin infection with streptococcus. There is a decline in the prevalence of the disease in childhood, whereas the significant proportion of cases afflicts adults, mainly the elderly...

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ژورنال

عنوان ژورنال: Nephron Clinical Practice

سال: 2011

ISSN: 1660-2110,1660-2110

DOI: 10.1159/000324180